• Survey of Endogenous Procalcitonin in Sepsis with Individual Sequencing (SEPSIS)

    Coming Soon

    The goal of this study is to evaluate changes in procalcitonin levels over time in canine patients surgically treated for sepsis secondary to an abdominal cause (i.e. ruptured intestine). Additional blood sample collection will also be performed to investigate for possible novel markers for sepsis using next generation sequencing for the future development of diagnostic test.

    Study Details
  • Dysbiosis Enhancing Linkage Towards Association with Canine Osteosarcoma (DEL-TACO)

    Coming Soon

    Intestinal dysbiosis has been associated with tumor progression of colorectal, lung, and breast cancer in human patients. To date, no studies have been published investigating the intestinal microbiome in dogs or humans with osteosarcoma (OSA). The objective of this study is to determine whether or not canine patients diagnosed with OSA have intestinal dysbiosis and if the presence of intestinal dysbiosis is associated with metastasis in these patients.

    Study Details
  • Ethos Precision Medicine Umbrella Study for Hemangiosarcoma (ePUSH)

    Coming Soon

    Ethos Discovery now seeks to deliver a highly advanced clinical trial program investigating the use of novel drugs for the treatment of Hemangiosarcoma (HSA) with the goal of curing this aggressive cancer. This study will ask if drugs specifically matched to the genomic subtypes of patients with HSA will result in improved outcomes.

    Study Details
  • Sorafenib for the Treatment of Solid Tumors in Dogs

    Currently Enrolling

    We have previously reported on the tolerability and hints of clinical activity of Sorafenib in dogs with cancer. This background provides a rationale for the further study of Sorafenib in dogs with cancer. In this study we seek to define an optimal dosing schedule for Sorafenib and will assess its tolerability and activity in dogs with solid tumors.

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  • Rapamycin for the Treatment of Hemangiosarcoma in Dogs

    Currently Enrolling

    Based on its reported tolerability in dogs (alone and in combination with chemotherapy) this study will ask whether Rapamycin may improve treatment outcomes for dogs with hemangiosarcoma, and more precisely, to understand the hemangiosarcoma genotypes which may most benefit from its use.

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  • Assay for DNA using Exosome for Pancreatitis Testing (ADEPT)

    Currently Enrolling

    This is study is looking to develop a novel diagnostic test for canine pancreatitis through the identification of genomic markers called exosomes.

    Study Details